Publications – Giulia Carli, PhD

2024

Oertel, W. H., Janzen, A., Henrich, M. T., Geibl, F. F., Sittig, E., Meles, S. K., Carli, G., … & Strupp, M. (2024). Acetyl-DL-leucine in two individuals with REM sleep behavior disorder improves symptoms, reverses loss of striatal dopamine-transporter binding and stabilizes pathological metabolic brain pattern. Nature Communications. https://doi.org/10.1038/s41467-024-51502-7
Bohnen, N. I., Marusic, U., Roytman, S., Paalanen, R., Michalakis, F., Brown, T., Scott, J.H., Carli, G., Albin, R.L., & Kanel, P. (2024). Dynamic balance and gait impairments in Parkinson’s disease: novel cholinergic patterns. Brain communications. https://doi.org/10.1093/braincomms/fcae286
Carli, G., Kanel, P., Roytman, S., Pongmala, C., Albin, R. L., Raffel, D. M., … & Bohnen, N. I. (2024). Noradrenergic cardiac denervation is associated with gait velocity in Parkinson disease: a dual ligand PET study. European Journal of Nuclear Medicine and Molecular Imaging. https://doi.org/10.1007/s00259-024-06822-7
Carli, G., Kanel, P., Michalakis, F., Roytman, S., Bohnen, J. L. B., Wigstrom, T. P., … & Bohnen, N. I. (2024). Cardiac sympathetic denervation and anxiety in Parkinson disease. Parkinsonism & Related Disorders. https://doi.org/10.1016/j.parkreldis.2024.106997
Carli, G., Roytman, S., & Bohnen, N. I. (2024). Correspondence: Concerns with the new biological research criteria for synucleinopathy. The Lancet Neurology. https://doi.org/10.1016/S1474-4422(24 )00222-9
Lövdal, S. S.*, Carli, G.*, Orso, B., Biehl, M., Arnaldi, D., Mattioli, P., … & Meles, S. K. (2024). Investigating the aspect of asymmetry in brain-first versus body-first Parkinson’s disease. npj Parkinson’s Disease. *These authors equally contributed. https://doi.org/10.1038/s41531-024-00685-3
Roytman, S., Paalanen, R., Carli, G., Marusic, U., Kanel, P., van Laar, T., & Bohnen, N. I. (2024). Multisensory mechanisms of gait and balance in Parkinson’s disease: an integrative review. Neural Regeneration Research. https://doi.org/10.4103/NRR.NRR-D-23-01484

2023

Bohnen, N. I., & Carli, G. (2023). Reader Response: Serial Nigrostriatal Dopaminergic Imaging in Mild Cognitive Impairment With Lewy Bodies, Alzheimer Disease, and Age-Matched Controls. Neurology.
Kanel, P., Carli, G., Vangel, R., Roytman, S., & Bohnen, N. I. (2023). Challenges and innovations in brain PET analysis of neurodegenerative disorders: a mini-review on partial volume effects, small brain region studies, and reference region selection. Frontiers in Neuroscience. https://doi.org/10.3389%2Ffnins.2023.1293847
Slingerland, S., van der Zee, S., Carli, G., Slomp, A. C., Boertien, J. M., Bohnen, N. I., … & Laar, T. V. (2023). Cholinergic innervation topography in GBA-associated de novo Parkinson’s disease patients. Brain. https://doi.org/10.1093/brain/awad323
Carli, G.*, Meles, S. K.*, Reesink, F. E., de Jong, B. M., Pilotto, A., Padovani, A., … & Perani, D. (2023). Comparison of univariate and multivariate analyses for brain [18F] FDG PET data in α-synucleinopathies. NeuroImage: Clinical. *These authors equally contributed. https://doi.org/10.1016/j.nicl.2023.103475
Carli, G., Meles, S. K., Janzen, A., Sittig, E., Kogan, R. V., Perani, D., … & the REMPET Working Group. (2023). Occipital hypometabolism is a risk factor for conversion to Parkinson’s disease in isolated REM sleep behaviour disorder. European Journal of Nuclear Medicine and Molecular Imaging. https://doi.org/10.1007/s00259-023-06289-y
Carli, G.*, Cavicchioli, M.*, Martini, A. L., Bruscoli, M., Manfredi, A., Presotto, L., … & Perani, D. (2023). Neurobiological Dysfunctional Substrates for the Self-Medication Hypothesis in Adult Individuals with Attention-Deficit Hyperactivity Disorder and Cocaine Use Disorder: A Fluorine-18-Fluorodeoxyglucose Positron Emission Tomography Study. Brain Connectivity. *These authors equally contributed. https://doi.org/10.1089/brain.2022.0076
D’Este, G., Berra, F., Carli, G., Leitner, C., Marelli, S., Zucconi, M., … & Galbiati, A. (2023). Cognitive Reserve in Isolated Rapid Eye-Movement Sleep Behavior Disorder. Brain sciences. https://doi.org/10.3390/brainsci13020176
Caminiti, S. P., & Carli, G. (2023). Molecular imaging evidence in favor or against PDD and DLB overlap. In Neuroimaging in Parkinson’s Disease and Related Disorders. https://doi.org/10.1016/B978-0-12-821651-4.00015-4

2022

Boccalini, C.*, Carli, G.*, Vanoli, E. G., Cocco, A., Albanese, A., Garibotto, V., & Perani, D. (2022). Manual and semi-automated approaches to MIBG myocardial scintigraphy in patients with Parkinson’s disease. Frontiers in Medicine. *These authors equally contributed. https://doi.org/10.3389/fmed.2022.1073720
Boccalini, C.*, Carli, G.*, Tondo, G., Polito, C., Catricalà, E., Berti, V., … & Perani, D. Brain metabolic connectivity reconfiguration in the semantic variant of primary progressive aphasia. Cortex. *These authors equally contributed. https://doi.org/10.1016/j.cortex.2022.05.010
Boccalini, C.*, Carli, G.*, Pilotto, A., Padovani, A., & Perani, D. Gender differences in dopaminergic system dysfunction in de novo Parkinson’s disease clinical subtypes. Neurobiology of Disease. *These authors equally contributed. https://doi.org/10.1016/j.nbd.2022.105668
Boccalini, C., Bortolin, E., Carli, G., Pilotto, A., Padovani, A., Ferini-Strambi, L., & Perani, D. Metabolic connectivity of resting-state networks in alpha synucleinopathies, from prodromal to dementia phase. Frontiers in Neuroscience. https://doi.org/10.3389/fnins.2022.930735
Martini, A. L.*, Carli, G.*, Kiferle, L., Piersanti, P., Palumbo, P., Morbelli, S., … & Sestini, S. Time‑dependent recovery of brain hypometabolism in neuro‑COVID‑19 patients. *These authors equally contributed. https://doi.org/10.1007/s00259-022-05942-2

2021

Caminiti, S. P.*, Carli, G.*, Avenali, M., Blandini, F., & Perani, D. Clinical and Dopamine Transporter Imaging Trajectories in a Cohort of Parkinson’s Disease Patients with GBA Mutations. Movement Disorders. *These authors equally contributed. https://doi.org/10.1002/mds.28818
Galbiati, A., Carli, G., Fasiello, E., Casoni, F., Zucconi, M., De Gennaro, L., … & Ferini-Strambi, L. Exploring the functional role and neural correlates of K-complexes in isolated rapid eye movement sleep behavior disorder. Cortex. https://doi.org/10.1016/j.cortex.2021.08.012
Beretta, L., Carli, G., Caffarra, P., & Perani, D. Distinct brain dysfunctions underlying visuo-constructive deficit in DLB and AD. Brain Imaging and Behavior. https://doi.org/10.1007/s11682-021-00515-7
Alongi, P., Chiaravalloti, A., Berti, V., Vellani, C., Trifirò, G., Puccini, G., Carli, G., … & Sestini, S. Amyloid PET in the diagnostic workup of neurodegenerative disease. Clinical and Translational Imaging. https://doi.org/10.1007/s40336-021-00428-x
Carli, G., Tondo, G., Boccalini, C., & Perani, D. Brain Molecular Connectivity in Neurodegenerative Conditions. Brain Sciences. https://doi.org/10.3390/brainsci11040433
Perani, D., Caminiti, S. P., Carli, G., & Tondo, G. PET Neuroimaging in Dementia Conditions. PET and SPECT in Neurology. https://doi.org/10.1007/978-3-030-53168-3_9
Boccalini, C., Carli, G., Pilotto, A., Padovani, A., Perani, D. Gender-related vulnerability of dopaminergic neural networks in Parkinson’s disease. Brain Connectivity. https://doi.org/10.1089/brain.2020.0781

2020

Carli, G., Caminiti, S. P., Sala, A., Galbiati, A., Pilotto, A., Ferini-Strambi, L., … & Perani, D. Impaired metabolic brain networks associated with neurotransmission systems in the α-synuclein spectrum. Parkinsonism & Related Disorders. https://doi.org/10.1016/j.parkreldis.2020.10.036
Tondo, G., Carli, G., Santangelo, R., Mattioli, M. V., Presotto, L., … & Perani, D. Biomarker-based definition of limbic-predominant long-lasting amnestic mild cognitive impairment. European Journal of Neurology. https://doi.org/10.1002/alz.037879
Carli, G., Boccalini, C., Vanoli, G., Filippi, M., Iannaccone, S., Magnani, G., & Perani, D. Specific occupational profiles as proxies of cognitive reserve induce neuroprotection in dementia with Lewy bodies. Brain Imaging and Behavior. https://doi.org/10.1007/s11682-020-00342-2
Carli, G., Caminiti, S. P., Galbiati, A., Marelli, S., Casoni, F., Padovani, A., … & Perani, D. In-vivo signatures of neurodegeneration in isolated rapid eye movement sleep behaviour disorder. European Journal of Neurology. https://doi.org/10.1111/ene.14215

2019

Malpetti, M., Carli, G., Sala, A., Cerami, C., Marcone, A., Iannaccone, S., … & Perani, D. Variant-specific vulnerability in metabolic connectivity and resting-state networks in behavioural variant of frontotemporal dementia. Cortex. https://doi.org/10.1016/j.cortex.2019.07.018
Galbiati, A., Carli, G., Dodich, A., Marelli, S., Pagnini, C., Cerami, C., … & Ferini-Strambi, L. Qualitative Scoring of the Pentagon Test: A Tool for the Identification of Subtle Cognitive Deficits in Isolated REM Sleep Behavior Disorder Patients. Archives of Clinical Neuropsychology. https://doi.org/10.1093/arclin/acz024

2018

Galbiati, A, Carli, G., Hensley, M., & Ferini-Strambi, L. REM Sleep Behavior Disorder and Alzheimer’s Disease: Definitely No Relationship? Journal of Alzheimer’s Disease. https://doi.org/10.3233/jad-171164
Ferini-Strambi, L., Carli, G., Casoni, F., & Galbiati, A. Restless legs syndrome and Parkinson’s disease: a causal relationship between the two disorders? Frontiers in Neurology. https://doi.org/10.3389/fneur.2018.00551
Dodich, A., Carli, G., Cerami, C., Iannaccone, S., Magnani, G., and Perani, D. Social and cognitive control skills in long-life occupation activities modulate the brain reserve in the behavioural variant of frontotemporal dementia. Cortex. https://doi.org/10.1016/j.cortex.2017.12.006